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- Hilldale Professorship – 2013
- Fellow of the American Academy of Microbiology – 2009
- Hugh M. Huffman Award – 2009
- Member, American Academy of Arts and Sciences – 2007
- Fellow, Biophysical Society – 2005
- Keynote Lecturer, 64th International Calorimetry Conference, Santa Fe, NM – 2004
- Keynote Lecturer, Gordon Research Conference on Osmoregulation, Bristol, RI – 2003
- Steenbock Professor of Chemical Sciences, UW-Madison – 2002-2012
- Biophysical Society Founders Award – 2001
- Founders Award Lecturer, Biophysical Society – 2001
- 6th Mississippi Chemical Lecture in Chemical Sciences, University of Mississippi – 2000
- Vilas Associate Award, UW-Madison – 1998-2000
- NIH Merit Award – 1997-2005
- Keynote Lecturer, Biopolymers Gordon Research Conference, Newport, RI – 1994
- Keynote Lecturer, 19th Annual Lorne Conference on Protein Structure and Function, Lorne, Australia – 1994
- Inaugural Stanley Gill Memorial Lecturer, University of Colorado – 1994
- Fellow, American Association for the Advancement of Science – 1991
- John D. Ferry Professor of Chemistry and Biochemistry, UW-Madison – 1990
- WARF-University Houses Professorship, UW-Madison – 1990
- Faculty Teaching Award, UW-Madison – 1986
- Dupont Distinguished Lecturer, University of Indiana – 1995
- Faculty Star Award, UW-Madison – 1984-1985
- Phi Beta Kappa Teaching Award, UW-Madison – 1976